Magnetomotive ultrasound imaging is a contrast agent technique that enables the imaging of iron oxide nanoparticles in tissue. Here, a local sinusoidal oscillating magnetic field is used to excite nanoparticles distributed in biological tissues to move and detect them with ultrasound techniques.
The imaging of nanoparticles represents a step towards functional ultrasound imaging. A possible coupling of nanoparticles and biological markers allows a variety of clinical applications.
The focus of research at our chair in the field of magnetomotive imaging is on the development of novel signal processing algorithms for the detection of nanoparticles. Since the magnetic forces acting on the nanoparticles are very small, the particles are moved only a few micrometers. The challenge in terms of signal processing is to detect such small movements with sufficient contrast-to-noise ratio.
Contacts: Tim Kranemann, Thomas Ersepke and Georg Schmitz